Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2007-04-10
2007-04-10
Webman, Edward J. (Department: 1616)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S488000
Reexamination Certificate
active
09233443
ABSTRACT:
A liquid encapsulant component which contains an active, sensitive encapsulant, such as a live microorganism or an enzyme dissolved or dispersed in a liquid plasticizer is admixed with a plasticizable matrix material. The matrix material is plasticizable by the liquid plasticizer and the encapsulation of the active encapsulant is accomplished at a low temperature and under low shear conditions. The active component is encapsulated and/or embedded in the plasticizable matrix component or material in a continuous process to produce discrete, solid particles. The liquid content of the liquid encapsulant component provides substantially all or completely all of the liquid plasticizer needed to plasticize the matrix component to obtain a formable, extrudable, cuttable, mixture or dough. Removal of liquid plasticizer prior to extrusion is not needed to adjust the viscosity of the mixture for formability. Release of an active component from the matrix may be delayed or controlled over time so that the active component is delivered when and where it is needed to perform its intended function. Controlled release, discrete, solid particles which contain an encapsulated and/or embedded component such as a heat sensitive or readily oxidizable pharmaceutically, biologically, or nutritionally active component are continuously produced without substantial destruction of the matrix material or encapsulant.
REFERENCES:
patent: 2876160 (1959-03-01), Schoch et al.
patent: 3027102 (1962-03-01), Lödige et al.
patent: 3404984 (1968-10-01), Olsen
patent: 3762931 (1973-10-01), Craig et al.
patent: 3786123 (1974-01-01), Katzen
patent: 3868471 (1975-02-01), Decelles et al.
patent: 3922354 (1975-11-01), Galluzzi et al.
patent: 3925343 (1975-12-01), Hampton et al.
patent: 3928567 (1975-12-01), Andersen et al.
patent: 3962416 (1976-06-01), Katzen
patent: 3992555 (1976-11-01), Kovacs
patent: 4075356 (1978-02-01), Haag et al.
patent: 4106991 (1978-08-01), Markussen et al.
patent: 4178392 (1979-12-01), Gobble et al.
patent: 4187321 (1980-02-01), Mutai et al.
patent: 4242219 (1980-12-01), Bogerman et al.
patent: 4379171 (1983-04-01), Furda et al.
patent: 4386106 (1983-05-01), Merritt et al.
patent: 4532145 (1985-07-01), Saleeb et al.
patent: 4689235 (1987-08-01), Barnes et al.
patent: 4816259 (1989-03-01), Matthews et al.
patent: 4871574 (1989-10-01), Yamazaki et al.
patent: 4886820 (1989-12-01), Gross et al.
patent: 4888171 (1989-12-01), Okonogi et al.
patent: 4895725 (1990-01-01), Kantor et al.
patent: 4999208 (1991-03-01), Lengerich et al.
patent: 5009900 (1991-04-01), Levine et al.
patent: 5023083 (1991-06-01), Drell
patent: 5064669 (1991-11-01), Tan et al.
patent: 5071668 (1991-12-01), van Lengerich et al.
patent: 5074902 (1991-12-01), Connick, Jr. et al.
patent: 5075058 (1991-12-01), Chan et al.
patent: 5079012 (1992-01-01), Lengerich et al.
patent: 5087461 (1992-02-01), Levine et al.
patent: 5106639 (1992-04-01), Lee et al.
patent: 5118513 (1992-06-01), Mehansho et al.
patent: 5183690 (1993-02-01), Carr et al.
patent: 5262167 (1993-11-01), Vegesna et al.
patent: 5296000 (1994-03-01), Darmont et al.
patent: 5314692 (1994-05-01), Haarasilta et al.
patent: 5320669 (1994-06-01), Lim et al.
patent: 5431929 (1995-07-01), Yatka et al.
patent: 5458823 (1995-10-01), Perkins et al.
patent: 5466460 (1995-11-01), McMahon et al.
patent: 5508053 (1996-04-01), Villota et al.
patent: 5514387 (1996-05-01), Zimmerman et al.
patent: 5567730 (1996-10-01), Miyashita et al.
patent: 5597416 (1997-01-01), Fuisz et al.
patent: 5683720 (1997-11-01), Myers et al.
patent: 5716615 (1998-02-01), Cavaliere-Vesely et al.
patent: 5744180 (1998-04-01), Cherukuri et al.
patent: 5750104 (1998-05-01), Sipos
patent: 5820903 (1998-10-01), Fleury et al.
patent: 5851553 (1998-12-01), Myers et al.
patent: 5862998 (1999-01-01), Bogue et al.
patent: 5894029 (1999-04-01), Brown et al.
patent: 5902617 (1999-05-01), Pabst
patent: 5939127 (1999-08-01), Abboud
patent: 5952033 (1999-09-01), Anantharaman et al.
patent: 5958502 (1999-09-01), Fulger et al.
patent: 5972373 (1999-10-01), Yajima et al.
patent: 5972395 (1999-10-01), Saleeb et al.
patent: 5972404 (1999-10-01), van Lengerich
patent: 5972415 (1999-10-01), Brassart et al.
patent: 5976603 (1999-11-01), Kota et al.
patent: 6004594 (1999-12-01), van Lengerich
patent: 6008027 (1999-12-01), Langner
patent: 6024994 (2000-02-01), Jacobson et al.
patent: 6048551 (2000-04-01), Hilfinger et al.
patent: 6149965 (2000-11-01), van Lengerich et al.
patent: 6168811 (2001-01-01), Clark et al.
patent: 6174553 (2001-01-01), Cerda et al.
patent: 6190591 (2001-02-01), van Lengerich
patent: 6242033 (2001-06-01), Sander
patent: 6261613 (2001-07-01), Narayanaswamy et al.
patent: 6284268 (2001-09-01), Mishra et al.
patent: 6342257 (2002-01-01), Jacobson et al.
patent: 6368621 (2002-04-01), Engel et al.
patent: 6436453 (2002-08-01), van Lengerich et al.
patent: 6468568 (2002-10-01), Leusner et al.
patent: 6500463 (2002-12-01), van Lengerich
patent: 2001/0008635 (2001-07-01), Quellet et al.
patent: 2001/0044026 (2001-11-01), Vaghefi et al.
patent: 37 38 042 (1988-05-01), None
patent: 40 21 678 (1992-01-01), None
patent: 40 41 752 (1992-06-01), None
patent: 33662 (1969-10-01), None
patent: 47014316 (1972-10-01), None
patent: 0 202 408 (1986-11-01), None
patent: 0 223 963 (1987-06-01), None
patent: 0 347 014 (1989-12-01), None
patent: 0 385 081 (1990-09-01), None
patent: 391518 (1990-10-01), None
patent: 0 462 012 (1991-12-01), None
patent: 0 465 364 (1992-01-01), None
patent: 552057 (1993-07-01), None
patent: 603992 (1994-06-01), None
patent: 605913 (1994-07-01), None
patent: 0 705 541 (1996-04-01), None
patent: 1064 856 (2001-01-01), None
patent: 1066 761 (2001-01-01), None
patent: 1 118 274 (2001-07-01), None
patent: 2 640 472 (1990-06-01), None
patent: 2 758 055 (1998-07-01), None
patent: 15312 (1911-01-01), None
patent: 1 437 501 (1976-05-01), None
patent: 59139317 (1984-08-01), None
patent: 63 173568 (1988-07-01), None
patent: 1313421 (1989-12-01), None
patent: 6024962 (1994-02-01), None
patent: 2000139372 (2000-05-01), None
patent: WO 85/04074 (1985-09-01), None
patent: WO 88/01512 (1988-03-01), None
patent: WO 90/15537 (1990-12-01), None
patent: 91 03940 (1991-04-01), None
patent: WO 92/00130 (1992-01-01), None
patent: WO 92/00140 (1992-01-01), None
patent: WO 92/12645 (1992-08-01), None
patent: WO 94/01001 (1994-01-01), None
patent: WO 94/23593 (1994-10-01), None
patent: WO 95/00121 (1995-01-01), None
patent: WO 95/18544 (1995-07-01), None
patent: WO 95/26752 (1995-10-01), None
patent: 96 09773 (1996-04-01), None
patent: 96 14058 (1996-05-01), None
patent: WO 97/16076 (1997-05-01), None
patent: WO 97/38016 (1997-10-01), None
patent: WO 97/39116 (1997-10-01), None
patent: WO 98/02148 (1998-01-01), None
patent: WO 98/09981 (1998-03-01), None
patent: WO 98/18610 (1998-05-01), None
patent: WO 98/35704 (1998-08-01), None
patent: WO 98/50019 (1998-11-01), None
patent: WO 98/54980 (1998-12-01), None
patent: WO 98/58642 (1998-12-01), None
patent: WO 99/11242 (1999-03-01), None
patent: WO 99/20745 (1999-04-01), None
patent: WO 99/45904 (1999-09-01), None
patent: WO 99/56563 (1999-11-01), None
patent: WO 99/61002 (1999-12-01), None
patent: WO 00/41740 (2000-07-01), None
patent: WO 00/64436 (2000-11-01), None
patent: WO 01/74175 (2001-10-01), None
Per Artusson et al., “Characterization of Polyacryl Starch Microparticles as Carriers for Proteins and Drugs,”Journal of Pharmaceutical Science, vol. 73, No. 11, pp. 1507-1513 (Nov. 1984).
Lennart Randen et al., “Coprecipitation of Enzymes with Water Soluble Starch—An Alternative to Freeze-drying,”J. Pharm. Pharmacol., vol. 40, pp. 763-766 (1988).
Shigeaki Maruo et al., “Effects of Moranoline, 4-O-β-D-Glucopyranosylmoranoline and TheirN-Substituted Derivatives on Thermostability of Cyclodextrin Glycosyltransferase, Glucoamylase, and β-Amylase,”Biosci. Biotech. Biochem., vol. 57, No. 8, pp. 1294-1298., (1993).
Wendell Q. Sun et al., “Protein stability in the amorphous carbohydrate matrix: relevance to anhydrob
General Mills Inc.
Hollander Barry I.
O'Toole John A.
Taylor Douglas J.
Webman Edward J.
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