Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1997-06-02
1999-07-20
Harrison, Robert H.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424484, 424488, 424489, A61K 914
Patent
active
059253819
ABSTRACT:
Multiple micro-encapsulations of a high concentration oleophilic substance using heat to set the primary particle renders the composition suitable for the production of free-flowing powders or beadlets. Microencapsulation involves forming an emulsion out of the oleophilic substance and a polymer, and then use heat setting and/or cross-linking the polymer encapsulates the oleophilic composition. This process is then repeated with a second polymer or third polymer, and with or without cross-linked via the same or different mechanism to further protect the oleophilic substance.
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Boyle Stasia
Chang Kuei-Tu
Harrison Robert H.
Johnston George W.
Roche Vitamins Inc.
Tramaloni Dennis P.
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