Encapsulation of living tissue cells in inorganic microspheres p

Details Encapsulation of living tissue cells in inorganic microspheres p Encapsulation of living tissue cells in inorganic microspheres p

1997-08-18

1999-04-20

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an...

435182, 435382, 435420, C12N 1114, C12N 1104, C12N 500

Patent

active

058957570

ABSTRACT:
Living tissue cells such as from an animal or a plant are encapsulated in inorganic microspheres. An organosilicon precursor such as tetraethoxysilane or an organometallic precursor such as aluminum tri-n-propoxide is hydrolyzed in an aqueous acidic solution to form a gel forming solution. Tissue cells are mixed with a salt solution such as Hanks' Balanced Salt Solution to form a solution containing the tissue cells. The solution containing tissue cells and the gel forming solution are mixed to form a mixture. The mixture is mixed with an oil that is immiscible with the mixture and has a lower specific density than the mixture. The resultant mixture is stirred to form microspheres encapsulating the tissue cells. The mixture containing the tissue cells and the gel forming solution may be formed into droplets and added to the top of a column containing the oil to form the microspheres.

REFERENCES:
patent: 4148689 (1979-04-01), Hino et al.
patent: 4391909 (1983-07-01), Lim
patent: 4797213 (1989-01-01), Parisims et al.
patent: 5200334 (1993-04-01), Dunn et al.
patent: 5693513 (1997-12-01), Pope
patent: 5739020 (1998-04-01), Pope
patent: 5744337 (1998-04-01), Price et al.

Affiliated with

Also associated with

Rating

Encapsulation of living tissue cells in inorganic microspheres p does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Encapsulation of living tissue cells in inorganic microspheres p, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Encapsulation of living tissue cells in inorganic microspheres p will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2247627