Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1988-12-20
1991-06-11
Lovering, Richard D.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
264 41, 4284022, 530399, 935 13, A61K 9127, A61K 3736, B01J 1302
Patent
active
050230867
ABSTRACT:
Encapsulated ionophore growth factors and methods of encapsulating these growth factors in lipid vesicles, particularly nonphospholipid paucilamellar lipid vesicles, have been discovered. These methods allow aqueous-based formulations of water-insoluble growth factors to be made.
REFERENCES:
patent: 3372201 (1968-03-01), Leary et al.
patent: 3957971 (1976-05-01), Oleniacz
patent: 4133874 (1979-01-01), Miller et al.
patent: 4182330 (1980-01-01), Michaels
patent: 4217344 (1980-08-01), Vanlerberghe et al.
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4241046 (1980-12-01), Papahadjopoulos et al.
patent: 4247411 (1981-01-01), Vanlerberghe et al.
patent: 4279894 (1981-07-01), Davies et al.
patent: 4348329 (1982-09-01), Chapman
patent: 4356167 (1982-10-01), Kelly
patent: 4377567 (1983-03-01), Geho
patent: 4485054 (1984-11-01), Mezei et al.
patent: 4536324 (1985-08-01), Fujiwara et al.
patent: 4544545 (1985-10-01), Ryan et al.
patent: 4551288 (1985-11-01), Kelly
patent: 4560665 (1985-12-01), Nakae et al.
patent: 4564599 (1986-01-01), Janoff et al.
patent: 4603044 (1986-07-01), Geho et al.
patent: 4608211 (1986-08-01), Handjani et al.
patent: 4610868 (1986-09-01), Fountain et al.
patent: 4619913 (1986-10-01), Luck et al.
patent: 4666711 (1987-05-01), Vanlerberghe et al.
patent: 4684625 (1987-08-01), Eppstein et al.
patent: 4692433 (1987-09-01), Hostetler et al.
patent: 4695554 (1987-09-01), O'Connell et al.
patent: 4708861 (1987-11-01), Popescu et al.
patent: 4721612 (1988-01-01), Janoff et al.
patent: 4725442 (1988-02-01), Haynes
patent: 4731210 (1988-03-01), Weder et al.
patent: 4744989 (1988-05-01), Payne et al.
patent: 4753788 (1988-06-01), Gamble
patent: 4772471 (1988-09-01), Vanlerberghe et al.
patent: 4855090 (1989-08-01), Wallach
patent: 4867980 (1989-09-01), Edwards et al.
patent: 4911928 (1990-03-01), Wallach
patent: 4917951 (1990-04-01), Wallach
Diffusion of Univalent Ions Across the Lamellae of Swollen Phospholipids, A. Bingham, et al., J. Mol. Biol. 13, 238-252 (1965).
McCutcheon's Detergents & Emulsifiers 1973 North American Edition, p. 27.
The Carrier Potential of Liposomes in Biology and Medicine (First of Two Parts), G. Gregoriadis, The New England Journal of Medicine, 295, 704-710 (1976).
Procedure for Preparation of Liposomes with Large Internal Acqueous Space and High Capture by Reverse-Phase Evaporation, F. Szoka, Jr. et al., Proc. Natl. Acad. Sct. USA 75, 4194-4198 (1978).
2. Methodes de Preparation des Liposomes, N. Douseet, et al., Puisieux and Delattre, Eds. Techniques et Documentation La Voisier Paris, pp. 41-72, (1985).
McCutcheon's Emulsifiers & Detergents 1982 North American Edition, pp. 76-77.
Liposomes, edited by Marc J. Ostro, The Liposome Co., Princeton, N.J., Marcel Dekker, Inc., New York and Basel, pp. 246-249 (1983).
A Very Mild Method Allowing the Encapsulation of Very High Amounts of Macromolecules into Very Large (1000 nm) Unilamellar Liposomes, Philippot, et al., Biochem. Biophys. Acta, 734, 137-143 (1983).
Bilayer Fluidity of Non-Ionic Vesicle. An Investigation by Differential, Polarized Phase Fluorometry, A. Ribier, et al., Colloids and Surfaces 10, 155-161 (1984).
The Preparation and Properties of Niosomes--Non-Ionic Surfactant Vesicles, A. Baillie, et al., J. Pharm. Pharmacol., 37, 863-888 (1985).
11. Les Niosomes, R. Handjani-Vila, et al., Les Liposomes, Puisieux and Delattre, Eds. Techniques et Documentation La Voisier Paris, pp. 297-313 (1985).
Extemporaneous Preparation of Large Unilammelar Liposomes, J. Philippot, et al., Biochem. Biophys. Acta, 821, 79-84 (1985).
Problemes technologiques poses par l'utilisation des liposomes comme vecteurs de substances medicamenteuses. Encapsulation, Sterilisation, Conservation, F. Puisieux, et al., Les Liposomes, Ed. Techniques et Documentation La Voisier Paris, pp. 73-113 (1985).
Non-Ionic Surfactant Vesicles, Niosomes, as a Delivery System for the Anti-Leishmanial Drug, Sodium Stibogluconate, A. Baillie, et al., J. Pharm. Pharmacol., 38, 502-505, (1986).
Lovering Richard D.
Micro-Pak, Inc.
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