Encapsulated co-micronized bicarbonate salt compositions

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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424 69, 424401, 424405, 424409, 424493, 424641, 424642, 424717, 424719, 424722, 514951, 514770, A01N 5900, A61K 914

Patent

active

054827205

ABSTRACT:
This invention provides an encapsulated co-micronized bicarbonate salt powder composition which is a blend of crystalline ingredients having a particle size between about 0.1-30 microns. The composition is produced by mill co-micronization of a crystalline bicarbonate ingredient and a crystalline inorganic compound ingredient having a Mohs hardness value between about 3-7, and then surface coating the particles with a polymer. A blend of crystalline particles such as sodium bicarbonate and zinc oxide is free-flowing and essentially free of agglomerated solids after co-micronization, and the discrete crystalline particles are coated with a polymer to form a present invention encapsulated co-micronized bicarbonate salt powder composition.

REFERENCES:
patent: 4302347 (1981-11-01), Straw et al.
patent: 5338551 (1994-08-01), Lajoie
patent: 5376362 (1994-12-01), Murphy et al.

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