Encapsulated antigenic tumor specific substances and methods for

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 7, 23230B, 424 12, C12Q 168, G01N 3354

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active

043438954

ABSTRACT:
The present invention provides encapsulated antigenic tumor-specific substances prepared by extracting said antigenic tumor-specific substances in an aqueous phase and then encapsulating said aqueous phase. Said encapsulated substances are characterized by a degree of antigenic activity such that when they are contacted with a composition of naturally tumor-sensitized lymphocytes taken from a host having cancer in the presence of macrophages, macrophage fusion occurs to form at least one multinucleated giant macrophage cell. The invention further provides diagnostic tests for the determination of cancer which utilize said strongly antigenic tumor-specific substances as reagents.

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