Enantioselective reformatsky process for preparing optically...

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C568S700000

Reexamination Certificate

active

06924386

ABSTRACT:
A process is provided for preparing optically active alcohols, amines and derivatives thereof by reacting aldehydes or imines at a temperature of less than 15° C. in the presence of a chiral, enantiomerically pure auxiliary with an organozinc halide which is obtained from zinc and a reactive halogen compound, and water, acid or base, or an alkylating, arylating, acylating or silylating reagent is subsequently added.

REFERENCES:
patent: 6417377 (2002-07-01), Pōchlauer et al.
patent: 1223 168 (2002-07-01), None
J.M. Andres, Y. Martin, R. Pedrosa, A. Perez-Encabo, Tetrahedron, 1997, 53, p. 3787.
M. Guetté, J. Capillon, J.P.-Guetté, Tetrahedron, 1973, 29, p. 3659.
D. Seebach, W. Langer, Helvetica, Chimica Acta, 1979, 62, p. 1701.
A. Ojida, T. Yamano, N. Taya, A. Tasaka, Org. Lett. 2002, 4, p. 3051.
Y. Ukaji, S. Takenaka, Y. Horita, K. Inomata, Chem. Lett. 2001, p. 254.
A. Fürstner, Synthesis. 1989, p. 571.
G. Picotin, P. Miginiac, J. Org. Chem., 1987, 52, p. 4796.
Y. Zhang, W. Wu, Tetrhedron, Asymmetry, 1997, 21, 3575-3578.
C. Jiang et al., Huaxue Tongbolo, 2001, 10, 637-640, STN[HCAPLUS]AN: 2001-817298.
R. Pedrosa et al., Tetrahedron, 2000, 56, 1217-23.
Y. Butsugan et al., J. Chem. Soc. Perkin Trans. 1, 1992, 711-713.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Enantioselective reformatsky process for preparing optically... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Enantioselective reformatsky process for preparing optically..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enantioselective reformatsky process for preparing optically... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3439487

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.