Enantioselective oxazaborolidine catalysts

Details Enantioselective oxazaborolidine catalysts Enantioselective oxazaborolidine catalysts

1999-04-26

2000-03-14

Ambrose, Michael G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

544229, 546 13, 546344, 548110, 549 4, 549213, 549403, 558289, 568705, 568808, 568812, 568814, C07C 29143, C07F 504

Patent

active

060375051

ABSTRACT:
The anantoselective borane reduction of prochiral ketones to optically pure alcohols is effectively achieved by performing the reduction in the precence of catalytic amounts of the new and valuable oxazaborolidine compounds of formulas (I) and (II). The compounds of formulas (I) and (II) may be isolated and purified prior to use in the reduction reactions or the compounds of formulas (I) and (II) may be generated in situ. ##STR1##

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