Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...
Patent
1984-11-13
1987-06-02
Rosen, Sam
Chemistry: molecular biology and microbiology
Process of utilizing an enzyme or micro-organism to destroy...
Resolution of optical isomers or purification of organic...
435106, 435197, C07P 4100
Patent
active
046703950
ABSTRACT:
Disclosed is combination of an acylase and esterase for selective enzymatic hydrolysis of only the L-isomer of an L and D mixture of .alpha.N-acyl-.alpha.-amino acid ester whose alpha carbon atom is chiral to yield a mixture containing L-.alpha.-amino acid and D-.alpha.-N-acyl-.alpha.-amino acid ester but essentially no D-.alpha.-amino acid.
REFERENCES:
patent: 3386888 (1968-06-01), Chibata et al.
patent: 3527671 (1971-09-01), Zenk et al.
patent: 3813317 (1972-03-01), Benoiton et al.
patent: 3816254 (1974-06-01), Chibata et al.
patent: 4108723 (1978-08-01), Hirohara et al.
Burrington James D.
Cesa Mark C.
Kung Wei-Jen
Evans Larry W.
Herald William J.
Lynch Charles S.
Miller John E.
Rosen Sam
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