Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1999-07-23
2000-09-19
Owens, Amelia
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
549445, C12P 700, C07D31744
Patent
active
061210269
ABSTRACT:
The invention relates to a class of enantiomerically pure intermediates represented by Formula I, where X is F, Cl, Br, or I, and a novel enantioselective bioreductive process using yeast to form these intermediates, which are useful in the synthesis of endothelin antagonists, and the like. ##STR1##
REFERENCES:
patent: 4147799 (1979-04-01), Obase et al.
patent: 5717116 (1998-02-01), Saito et al.
Obase, H. et al "1-(3,4-methylenedioxyphenyl)-2-alkylaminoethanol Derivatives" CA 78:136260 (1973).
Saito, K. et al "Process for Producing (R)-Styrene Oxides" CA 125:273737 (1991).
Chartrain Michel M.
Devine Paul N.
Krulewicz Barbara A.
Tschaen David M.
Camara Valerie J.
Daniel Mark R.
Merck & Co. , Inc.
Owens Amelia
LandOfFree
Enantioselective bioreduction using yeast does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Enantioselective bioreduction using yeast, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enantioselective bioreduction using yeast will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1071470