Enantioselection of amines using homocarbonates with hydrolase

Details Enantioselection of amines using homocarbonates with hydrolase Enantioselection of amines using homocarbonates with hydrolase

1996-01-24

1999-11-09

Saucier, Sandra E.

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435128, C07C 104

Patent

active

059812672

ABSTRACT:
Racemic amines are enzymically converted by enantioselective carbamation to produce to chiral carbamates. Simple homocarbonates employed as substrates. The chiral carbamates may then be deprotected to yield the original amine in a chiral form. Alternatively, the chiral carbamates may be reduced so as to produce methylated chiral amines.

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