Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-26
1997-04-01
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548448, A61K 3140, C07D20988
Patent
active
056166036
ABSTRACT:
A (+)or (-) enantiomer of a compound of formula (I) wherein R.sup.4 is methyl or ethyl, or a salt, solvate or hydrate thereof, processes for preparing said compounds and pharmaceutical compositions containing them. Compounds of formula (+) are 5-HT.sub.1 -like agonists.
REFERENCES:
patent: 4257952 (1981-03-01), Mooradian
Hacksell et al., "Chirality in drug research and design", Trends in Biotechnology, vol. 11, pp. 73-74 (1993).
Ariens, "Nonchiral, homochiral and composite chiral drugs", Trends in Pharmacological Sciences, vol. 14, pp. 68-75 (1993).
Borrett Gary T.
Kitteringham John
Porter Roderick A.
Shipton Mark R.
Vimal Mythily
King William T.
Lentz Edward T.
Ramsuer Robert W.
SmithKline Beecham Plc
Stein-Fernandez Nora
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