Enantiomerically selective biocatalyzed acylation

Details Enantiomerically selective biocatalyzed acylation Enantiomerically selective biocatalyzed acylation

1990-10-02

1991-10-15

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

435129, C07D205085, C12P 1716, C07B 4306

Patent

active

050576070

ABSTRACT:
An enantiomerically selective process for acylating racemic 3-amino azetidinone intermediates is provided using penicillin G amidase(acylase) as biocatalyst.

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M. Cole, J. Biochem (1969) 115, p. 741.
Kaufmann et al., Proceeding of the Conference on Antimicrobial Agents, 1960 p. 1-5.
Bondareva et al., Biokhimiya, vol. 34, No. 3, pp. 478-482 (1969).
J. G. Shwalae et al., Process Biochem., 24 (4) p. 146 (1989).

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