Enantiomerically pure pyridylcycloalkylethylamines and the salts

Details Enantiomerically pure pyridylcycloalkylethylamines and the salts Enantiomerically pure pyridylcycloalkylethylamines and the salts

1995-08-10

1998-06-16

Owens, Amelia

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21338

Patent

active

057672792

ABSTRACT:
The present invention relates to new enantiomerically pure pyridylcycloalkylethylamines of formula 1a and 1b, the salts thereof as well as to methods of preparing them and their use as intermediate products. ##STR1##

REFERENCES:
Falorni et al., "Chiral Ligands Containing Heteroatoms; 9. General Procedures For the Synthesis of Optically Active 1-(2-Pyridyl)alkylamines from .alpha.-Amino Acids", Synthesis, pp. 972-976 (1972).
Lazer et al., "Benzoxazolamines and Benzothiazolamines: Potent, Enantioselective Inhibitors of Leukotriene Biosynthesis with a Novel Mechanism of Action", J. Chem. Ed. 37, pp. 913-923 (1994).
Miao et al., "A Simple and Effective Enantiomeric Synthesis of a Chiral Primary Amine", Tetrahedron Letters, 34, pp. 2259-2262 (1993).
Miao et al., "The Resolution of Racemic Amides by the Formation of Diasteromeric Amides with Amino Acids", OPPI Briefs, pp. 87-91 (1992).
Mi et al., Chemical Abstracts, vol. 119. No. 7, Abstract No. 72857h (1993).

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