Enantiomerically pure intermediates for (quinolin-2-yl-methoxy)

Details Enantiomerically pure intermediates for (quinolin-2-yl-methoxy) Enantiomerically pure intermediates for (quinolin-2-yl-methoxy)

1993-12-08

1995-12-05

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514311, C07D21518, C07D21520, C07D21538, A61K 3147

Patent

active

054730767

ABSTRACT:
(Quinolin-2-yl-methoxy)phenylacetic acids are known as inhibitors of enzymatic reactions in the context of arachidonic acid metabolism. Enantiomerically pure (quinolin-2-yl-methoxy)phenylacetic acids can be prepared in a simple manner and in high purity and yield by diastereoselective alkylation of corresponding (quinolin-2-yl-methoxy)phenylacetic acid menthyl esters and subsequent specific removal of the ester radical with acids.

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