Enantiomerically pure atomoxetine and tomoxetine mandelate

Details Enantiomerically pure atomoxetine and tomoxetine mandelate Enantiomerically pure atomoxetine and tomoxetine mandelate

2005-06-28

2008-10-21

Davis, Brian J (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C514S651000

Reexamination Certificate

active

07439398

ABSTRACT:
The present invention provides enantiomerically pure (R)-(−)-tomoxetine (S)-(+)-mandelate and atomoxetine HCl. The present invention further provides enantiomerically pure (R)-(−)-tomoxetine (S)-(+)-mandelate prepared from racemic tomoxetine. The present invention also provides enantiomerically pure atomoxetine HCl prepared from (R)-(−)-tomoxetine (S)-(+)-mandelate.

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