Enantiomerically pure 2-oxa-5,8-diazabicyclo[4.3.0]nonanes and p

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D49804

Patent

active

054363349

ABSTRACT:
The invention relates to enantiomerically pure 2-oxa-5,8-diazabicyclo[4.3.0]nonanes and processes for their preparation.
The starting, intermediate and end products are as follows: ##STR1##

REFERENCES:
patent: 4634775 (1987-01-01), Beck et al.
patent: 4990517 (1991-02-01), Petersen et al.
Conant, The Chemistry of Organic Compounds, 5th ed. (1959), p. 333.
Patai, The Chemistry of the ether linkage Interscience, 1967, G. Kohnstam and D. K. H. Williams, pp. 118-120.
Patai, The Chemistry of the Sulphonium group Interscience, 1981, D. C. Dittmer & B. H. Patwardham, pp. 394-395; and Brandsma and Arens, pp. 591-594.
Gundermann Angew. Chem. Internat. Edit., vol. 2, 1963, No. 11, pp. 674-683.
H. Perst, Oxanium Ions in Organic Chemistry Weinheim, (1971) p. 101.
Chem. Pharm. Bull. 17(5) 980-086 (1969); Syntheses of 3,4-Epoxy- and 3,4-Epimino-pyrrolidines), Oida et al.
Zh. Org. Khim. 3, 1509 (1967); Synthesis of Pyrrolidine, Pyrroline, and Pyrrole Derivatives Based on Sulfur Arysulfonylmonoimino Dioxides., Levchenko et al.
J. Chem. Research (S), 1989, 224-225; Applications of Phase Transfer Catalysis. Part 47. Relative Stabilities and Performances of Various Phase Transfer Catalysts., Dehmlow et al.
Academic Press, (1978), pp. 217-220; Phase Transfer Catalysis, Starks.
Angew. Chem 92, 14-25 (1980); Chromatographische Racemattrennung, Blaschke.
Tsien et al., 1988, Trends in Neurol. Sci., 11:431-438.
Tanabe et al., 1987, Nature 328:313-318.
Singer et al., 1991, Science 253:1553.
Lacerda et al., 1991, Nature 352:527.
Veradi et al., 1991, Nature 352:159.
Ruth et al., 1989, Science 245:1115.
Gluzman, 1981, Cell 23:175.
Chen et al., 1987, Mol. Cell. Biol. 7:2745-2752.
Messing et al., 1985, J. Pharmacology and Exp. Therapeutics 235:407-411.
Rosario et al., 1989, Neurosci. 29, 735-747.
Carbone et al., 1990, Pflugers Arch., 416:170-179.
Zernig et al., 1986, Eur. J. Pharmacol. 128, 221-229.
Yool and Schwarz, 1991, Nature 349:700-704.
P. A. Powers et al., "Skeletal Muscle . . . Single Gene", The Journal of Biological Chemistry, vol. 267, No. 32, 15 Nov. 1992, pp. 22967-22972.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Enantiomerically pure 2-oxa-5,8-diazabicyclo[4.3.0]nonanes and p does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Enantiomerically pure 2-oxa-5,8-diazabicyclo[4.3.0]nonanes and p, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enantiomerically pure 2-oxa-5,8-diazabicyclo[4.3.0]nonanes and p will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-740434

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.