Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1992-10-14
1993-10-26
Dees, Jose G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
558414, 560 56, 560 57, 560 60, 560100, 560101, 560105, C07B 5700
Patent
active
052568164
ABSTRACT:
A process for obtaining a substantially pure enantiomer of an aryl-substituted aliphatic carboxylic acid is described. In this process, the aryl-substituted aliphatic carboxylic acid is reacted with an inorganic base in the presence of an organic base to substantially enrich the precipitate in one of the enantiomers and an improved yield. Substantially pure, enantiomeric salt is separated, leaving a mother liquor comprising the solvent and aryl-substituted aliphatic carboxylic acid enriched in the other enantiomer.
REFERENCES:
patent: 4831147 (1989-05-01), Russell
patent: 4865770 (1989-09-01), Piselli
patent: 4910309 (1990-03-01), Kershner et al.
patent: 4931587 (1990-06-01), Piselli
patent: 4973745 (1990-11-01), Blaschke et al.
Collet et al., Chem. Res. 80(3), 215-230, (1980).
Jaques et al., Enantiomers, Racemates and Resolutions, Chapter 3, J. Wiley & Sons, New York, N.Y., (1981), pp. 167-213.
Collet, A., pp. 91-110, Problems and Wonders of Chiral Molecules, Simonyi, M. (Ed.), Akademiai Keado, Budapest (1990).
Choudhury Azfar A.
Murray William T.
Patil Deepak R.
Young Robert E.
Clarke Vera C.
Dees Jos,e G.
Ethyl Corporation
LandOfFree
Enantiomeric resolution does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Enantiomeric resolution, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enantiomeric resolution will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-960591