Enantiomeric enrichment and stereoselective synthesis of chiral

Details Enantiomeric enrichment and stereoselective synthesis of chiral Enantiomeric enrichment and stereoselective synthesis of chiral

1989-06-22

1990-08-21

Rosen, Sam

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435128, 435148, C12P 1300, C12P 726

Patent

active

049506064

ABSTRACT:
Amines in which the amino group is on a secondary carbon atom which is chrially substituted can be enantiomerically enriched by the action of an omega-amino acid transaminase which has the property of preferentially converting one of the two chiral forms to a ketone. The process also can be used to stereoselectively synthesize one chiral form from ketones substantially to the exclusion of the other.

REFERENCES:
patent: 4806473 (1989-02-01), Johansen et al.
Cooper et al.--Chem Abst., vol. 103, (1985), p. 137,560X.
Chia et al.--Chem. Abst., vol. 101, (1984), p. 68342X.
Yonaha et al., Agric. Biol. Chem., 41 (9), 1701-1706, (1977).
Yonaha et al., Agric. Biol Chem., 42 (12), 2362-2367, (1978).
Yonaha et al., Agric. Biol. Chem., 47 (10), 2257-2265, (1983).
Nakano et al., J. Biochem., 81, 1375-1381, (1977).
Burnett et al., J.C.S. Chem. Comm., 1979, 826-828.
Tanizawa et al., Biochem. 21, 1104-1108, (1982).
Waters et al., FEMS Micro Lett., 34 (1986), 279-282.
Cooper et al., Arch. Biochem. Biophs., 239, 556-566, (1985).
Chia et al., Life Sciences, 34, 2443-2452.
"Enzyme Nomenclature", Academic Press, Inc., (1984), pp. 220-231.
"Vitamin B.sub.6 Pyridoxal Phosphate", D Dolphin et al., Ed., John Wiley & Sons, pp. 117 & 118.

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