Enantiomeric enrichment and stereoselective synthesis of chiral

Details Enantiomeric enrichment and stereoselective synthesis of chiral Enantiomeric enrichment and stereoselective synthesis of chiral

1992-10-09

1994-04-05

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435129, 435148, 435149, C12P 1302, C12P 726, C12P 738

Patent

active

053004370

ABSTRACT:
Amines in which the amino group is on a secondary carbon atom which is chirally substituted can be enantiomerically enriched by the action of an omega-amino acid transaminase which has the property of preferentially converting one of the two chiral forms to a ketone. The process also can be used to stereoselectively synthesize one chiral form from ketones substantially to the exclusion of the other.

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