Enantiomeric compounds with antibacterial activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S312000, C514S310000, C546S114000, C546S153000

Reexamination Certificate

active

07973050

ABSTRACT:
Novel compounds in enantiomeric excess that are inhibitors of bacterial methionyl synthetase (MetRS) are disclosed. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, and in particular their use in therapy forClostridium difficileinfection.

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