Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus containing
Reexamination Certificate
2008-01-29
2008-01-29
Eyler, Yvonne (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Phosphorus containing
C568S013000, C568S014000
Reexamination Certificate
active
07323601
ABSTRACT:
Unsaturated alkyllysophosphonocholines compounds of formula (I) or (II):or pharmaceutically-acceptable salts, prodrugs or isomers thereof. The compounds of the invention have anti-neoplastic activity, and accordingly have utility in treating cancer and related diseases. The invention also provides enantiomers of these compounds, as well as synthetic methods for producing an enantiomer, substantially free of the other enantiomer. Also disclosed are pharmaceutical compositions, as well methods for treating cancer with the pharmaceutical compositions.
REFERENCES:
patent: 2605280 (1952-07-01), Klotz et al.
Arthur Gilbert
Bittman Robert
Byun Hoe-Sup
Eyler Yvonne
Nixon & Vanderhye P.C.
Research Foundation of the City University of New York
The University of Manitoba
Valenrod Yevgeny
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