Enanitomers of unsaturated alkyllysophosphonocholines and...

Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus containing

Reexamination Certificate

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Details

C568S013000, C568S014000

Reexamination Certificate

active

07323601

ABSTRACT:
Unsaturated alkyllysophosphonocholines compounds of formula (I) or (II):or pharmaceutically-acceptable salts, prodrugs or isomers thereof. The compounds of the invention have anti-neoplastic activity, and accordingly have utility in treating cancer and related diseases. The invention also provides enantiomers of these compounds, as well as synthetic methods for producing an enantiomer, substantially free of the other enantiomer. Also disclosed are pharmaceutical compositions, as well methods for treating cancer with the pharmaceutical compositions.

REFERENCES:
patent: 2605280 (1952-07-01), Klotz et al.

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