Enaminone esters

Details Enaminone esters Enaminone esters

1993-03-02

1995-11-21

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

544164, 546223, 560 21, 560 34, 560 35, 560 45, 560 47, 560 48, 560125, 564168, 564374, 564391, 564431, 568346, A61K 3124

Patent

active

054687756

ABSTRACT:
The present invention concerns enaminones having the formula: ##STR1## wherein R is from the group consisting of COOCH.sub.3 and COOC.sub.2 H.sub.5 ; R.sup.1 is from the group consisting of H and CH.sub.3 ; R.sup.2 is from the group consisting of H when R.sup.1 is CH.sub.3 and CH.sub.3 when R.sup.1 is H; and R.sup.3 is from the group of first radicals consisting of benzyl, phenethyl, disubstituted phenyl and trisubstituted phenyl. The substituted species are second radicals having positive lipophilicity selected from the group consisting of F, Cl, Br, and I.

REFERENCES:
Edafiogho, J. Med. Chem., 35, pp. 2798-2805 (Jul. 24, 1992).

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