Enamines, pharmaceutical compositions, methods, synthetic proces

Details Enamines, pharmaceutical compositions, methods, synthetic proces Enamines, pharmaceutical compositions, methods, synthetic proces

1982-11-05

1984-08-07

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546284, 548336, 548374, 548527, 549 75, 549 77, 549 78, 549 79, 544146, 544379, C07D41706

Patent

active

044645368

ABSTRACT:
Antiinflammatory compounds of the following formula are disclosed: ##STR1## wherein R is lower alkyl; R.sup.1 is selected from the group consisting of lower alkyl, benzyl, and N,N-dimethylaminoethyl; or R and R.sup.1 are fused to form an optionally-substituted five- or six-membered heterocyclic ring; and X is hydrogen, methyl or halogen; and pharmaceutically acceptable acid addition salts thereof. Pharmaceutical compositions containing the antiinflammatory compounds and methods of using the antiinflammatory compounds are also described as are a synthetic process and synthetic intermediates for preparing the antiinflammatory compounds.

REFERENCES:
patent: 4128664 (1978-12-01), Moore
patent: 4172082 (1979-10-01), Moore
patent: 4357345 (1982-11-01), Moore

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