Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Derived from musculoskeletal system – other than cardiac muscle
Reexamination Certificate
2011-03-01
2011-03-01
Ford, Allison M (Department: 1651)
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Derived from musculoskeletal system, other than cardiac muscle
C424S548000, C514S002600, C514S021800
Reexamination Certificate
active
07897180
ABSTRACT:
The present invention relates to the use of a preparation of an active enamel matrix substance, such as an amelogenin, for the manufacture of a pharmaceutical composition for modulating an immune response. The composition can be used in preventing and/or treating a condition or disease in a mammal that is characterised by said mammal presenting an imbalance in its native immune response to an internal and/or external stimuli, i.e. wherein at least a part of said mammal's immune system is stimulated non-discriminatingly, reacts hypersensitively to said immunogen, or fails to react to said stimuli. Said condition can typically either be systemic or local, such as a systemic and/or post-traumatic whole-body inflammation or an autoimmune disease.
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P. Nikolopoulos et al., “J. Clin. Periodontol”, 25:715-720 (1998).
S. Foster, “Journal Of Bacteriology”, 174(s): 464-470 (1992).
S. Gestrelius et al., “J. Clin Periodontol”, 24:685-692 (1997).
A. Hoang, et al., “Periodontol”, 71(8):1270-1277 (2000).
Gestrelius Stina
Lyngstadaas Petter
Ford Allison M
Institut Straumann AG
Rissman Hendricks & Oliverio LLP
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