Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1994-06-02
1996-11-05
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
424900, 514492, 514502, 514836, 5149308, 556 50, 556 55, 556 63, 556 77, 556105, 556116, 556134, 556148, 534 16, 436173, A61B 5055
Patent
active
055714986
ABSTRACT:
Emulsions of paramagnetic contrast agents, and processes of making and using them are disclosed. The emulsions contain water, a dispersed oil phase and a complex of a paramagnetic metal ion and an organic chelator having a C.sub.10 -C.sub.30 unsaturated aliphatic group. The emulsions are very stable and therapeutically acceptable for intravenous administration to enhance MRI.
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Cacheris William P.
Grabiak Raymond C.
Kaufman Robert J.
Richard Thomas J.
HemaGen/PFC
Hollinden Gary E.
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