Compositions – Preservative agents – Anti-corrosion
Patent
1995-04-07
1997-01-21
Lovering, Richard D.
Compositions
Preservative agents
Anti-corrosion
2065243, 252314, 4284022, 514832, 514938, B01J 1300
Patent
active
055956874
ABSTRACT:
An injectable physiologically acceptable aqueous phase fluorocarbon emulsion, which has substantially no free fluorocarbon, has an excellent stability is prepared by a process of the invention. Typically, more than about 99.8 wt. % of the fluorocarbon remains in the size range of about 0.2 to 0.4 microns even after being stored at room temperature for one year or more in sealed containers under a non-oxidizing atmosphere. The emulsion is useful in medical applications, for example, coronary angioplasty, cancer therapy, among others.
REFERENCES:
patent: 2504482 (1950-04-01), Goldman
patent: 3823091 (1974-07-01), Samejima et al.
patent: 3911138 (1975-10-01), Clark, Jr.
patent: 3958014 (1976-05-01), Watanabe et al.
patent: 3962439 (1976-06-01), Yokoyama et al.
patent: 3989843 (1976-11-01), Chabert et al.
patent: 3993581 (1976-11-01), Yokoyama et al.
patent: 4252827 (1981-02-01), Yokoyama et al.
patent: 4369127 (1983-01-01), Cormier et al.
patent: 4423077 (1983-12-01), Sloviter
patent: 4443480 (1984-04-01), Clark, Jr.
patent: 4497892 (1985-02-01), Anderson
patent: 4591593 (1986-05-01), Yokoyama et al.
patent: 4713459 (1987-12-01), Yokoyama et al.
patent: 4722904 (1988-02-01), Feil
patent: 4865836 (1989-09-01), Long, Jr.
patent: 4866096 (1989-09-01), Schweighardt
patent: 4927623 (1990-05-01), Long, Jr.
patent: 4981691 (1991-01-01), Osterholm et al.
patent: 4987154 (1991-01-01), Long, Jr.
patent: 5335769 (1994-08-01), Klokkers-Bethke et al.
"Unemulsified Fluorocarbon", Application of Computer-Based Experimental Design to Optimization of Processing Conditions . . . , G. K. Hanna et al., Alliance Phar. Corp., San Diego, CA. Biomat., Art. Cells & Immob. Biotech., 20(2-4), 849-852, 1992.
"Properites of Polyorganosiloxane Surfaces on Glass", M. J. Hunter et al., Dow Corning Corp., Midland, MI Industrial & Engineering Chemistry, vol. 39, No. 11, Nov. 1947, pp. 1389-1395.
Dettre Robert H.
Raynolds Stuart
Lovering Richard D.
Thomas Jefferson University
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