Empty major histocompatibility class II heterodimers

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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435 693, 4353201, 530395, 530403, 530868, 4241841, 4241851, 4241931, 514 8, C12N 506, C12N 510, C07K 1474

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active

055830315

ABSTRACT:
The invention features an isolated sample of mammalian class II major histocompatibility heterodimers which are membrane-associated or in soluble form, and which are capable of binding added antigenic peptide; methods for producing large amounts of the soluble or membrane-associated histocompatibility protein by expression of DNA encoding the .alpha. and .beta. polypeptides; and methods for loading these heterodimers with any desired antigen.

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