Embryonic stem cell lines obtained from C3H/HeN and DBA/1J mouse

Details Embryonic stem cell lines obtained from C3H/HeN and DBA/1J mouse Embryonic stem cell lines obtained from C3H/HeN and DBA/1J mouse

1997-05-20

1999-11-16

Stanton, Brian R.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Rodent cell, per se

435325, C12N 500, C12N 506

Patent

active

059856599

ABSTRACT:
Embryonic stem cells derived from an inbred mouse strain selected from the group consisting of C3H/HeN, C57BL/6N, DBA/1J, and BALB/c strains, for example, C-2 cell having the accession number FERM BP-5933 and C-6 cell having the accession number FERM BP-5934 are disclosed. The embryonic stem cells of the present invention are derived from genetically complete inbred strains, and therefore, they are extremely useful for close genetic research.

REFERENCES:
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Lee et al. Cancer Research, 51:3257-3260.
H. Suemori et al., "Establishment of the Embryo-derived Stem (ES) Cell Lines from Mouse Blastocysts: Effects of the Feeder Cell Layer", Develop. Growth and Differ., vol. 29, No. 2, pp. 133-139 (1987).
M. Roach et al., "A New Embryonic Stem Cell Line from DBA/1 lacJ Mice Allows Genetic Modification in a Murine Model of Human Inflammation", Experimental Cell Research, vol. 221, pp. 520-525 (1995).
E. Kawase et al., "Strain Difference in Establishment of Mouse Embryonic Stem (ES) Cell Lines", Int. J. Dev. Biol., vol. 38, pp. 385-390 (1994).
N. Noben-Trauth et al., "Efficient Targeting of The IL-4 Gene in a BALB/c Embryonic Strem Cell Line", Transgenic Research, vol. 5, pp. 487-491 (1996).
H. Kitani et al., "Isolation of a Germline-Transmissible Embryonic Stem (ES) Cell Line from C3H/He Mice", Zoological Science, vol. 13, pp. 865-871 (1996).

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