Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-07-31
1999-12-21
Spector, Lorraine
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
530350, 536 231, 536 235, 4353201, 435325, 4352523, 43525411, 514 12, C07K 14435, C12N 1509, C12N 1512, C12N 1510
Patent
active
06004778&
ABSTRACT:
The invention provides a human embryogenesis protein (EMPRO) and polynucleotides which identify and encode EMPRO. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of EMPRO.
REFERENCES:
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Lee, J.J. et al., "Identification and characterization of a novel, evolutionarily conserved gene disrupted by the murine H.beta.58 embryonic lethal transgene insertion", Development, 115: 277-288 (1992) (GI 252483).
Lerner et al., Antibodies of predetermined specificity in biology and medicine, Adv. Immunol., 36: 1-45, 1984.
GenBank Accession No. R13708, clone 27086, accessed Jun. 22, 1998, Apr. 1995.
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Stratagene Cloning Systems 1994, Stratagene Cloning Systems:California, pp. 28, 57, 304, 1994.
McCabe et al., Developmentally regulated neural protein EAP-300 is expressed by myocardium and cardiac neural creast during chick embryogenesis, Dev. Dynamics, 203: 51-60, 1995.
GenBank Accession No. H22284, accessed Dec. 8, 1998, Jul. 1995.
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Bandman Olga
Corley Neil C.
Lal Preeti
Incyte Pharmaceuticals Inc.
Kaufman Claire M.
Spector Lorraine
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