Embolization using degradable crosslinked hydrogels

Details Embolization using degradable crosslinked hydrogels Embolization using degradable crosslinked hydrogels

2003-03-14

2010-11-23

Wax, Robert A (Department: 1615)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C560S312000, C526S328000, C424S422000

Reexamination Certificate

active

07838699

ABSTRACT:
One aspect of the present invention relates to a method of temporarily embolizing a blood vessel using a hydrolytically degradable crosslinked hydrogel as an embolus. In certain embodiments, the hydrolytically degradable crosslinked hydrogel substantially hydrolyzes only at about physiological pH. In certain embodiments of the method, the hydrolytically degradable crosslinked hydrogel is stable at low pH. In certain embodiments of the method, the hydrolytically degradable crosslinked hydrogel comprises a marker molecule, such as a dye, radiopaque, or an MRI-visible compound. It is to be understood that both the foregoing general description and the following detailed description are exemplary, and are intended to provide further explanation of the invention as claimed.

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International Search Report Completed on Jul. 25, 2003 and mailed on Aug. 18, 2003.

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