Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Rod – strand – filament or fiber
Patent
1994-03-16
1999-10-12
Yamnitzky, Marie
Stock material or miscellaneous articles
Coated or structually defined flake, particle, cell, strand,...
Rod, strand, filament or fiber
428370, 428371, 428398, 428903, 424450, 424451, 514 44, 514772, 264 4, 264 41, 264 46, B32B 100, A61K 900, B01J 1300
Patent
active
059652586
ABSTRACT:
Microstructures formed from fluorinated amphiphiles and mixed fluorinated and non-fluorinated amphiphiles and having the geometry of tubules, helixes and fibers and methods for preparing them. Tubular forms are capable of encapsulating or incorporating bioactive agents or other useful substances for controlled release in vivo.
REFERENCES:
patent: 4877501 (1989-10-01), Schnur et al.
Burke, Thomas G. et al (1987) Entrapment of 6-carboxyfluorescein within cylindrical phospholipid microstructures. Ann. N.Y. Acad. Sci. 507:330-333.
Frankel, David A., and O'Brien, David F. (1991) Supramolecular assemblies of diacetylenic aldonamides. J. Am. Chem. Soc. 113:7436-7437.
Frezard, Frederic et al (1994) Permeability and stability in buffer and in human serum of fluorinated phospholipid-based liposomes. Biochim. Biophys. acta. 1192:61-70.
Fuhrhop, J.H. et al (1993) Micellar rods and vesicular tubules made of 14"',16"'-diaminoporphyrins. J. Am. Chem. Soc. 115:11036-11037.
Fuhrhop, J.H. et al (1991) Supramolecular assemblies, a crystal structure, and a polymer of N-diacetylenic gluconamides. 113:7437-7439.
Fuhrhop, J.H. et al (1993) Fluid and solid fibers made of lipid molecular bilayers. Chem. Rev. 93:1565-1582.
Fuhrhop, J.H. et al (1987) The chiral bilayer effect stabilizes micellar fibers. J. Am. Chem. Soc. 109:3387-3390.
Greiner, J. et al (1993) Fluorinated surfactants intended for biomedical uses. Organofluorine Compounds in Medicinal Chemistry and Biomedical Applications 339-380.
Ishiwaka, Yuichi et al (1990) Direct observation of helices and vesicles of ammonium bilayers by high-resolution, scanning electron microscopy. Chemistry Letters 25-28.
Jacquemain, Didier et al (1992) Correlation between observed crystalline self-assembly of fluorocarbon and hydrocarbon amphiphiles at the air-water interface and calculated lattice energy. Determination of electrostatic properties of the CF.sub.2 group from a low-temperature x-ray diffraction study of perfluoroglutaramide. J. Am. Chem. Soc. 114:9983-9989.
Kimizuka, Nobuo et al (1990) Bilayer membranes of four-chained ammonium amphiphiles. Chemistry Letters 29-32.
Kraft, Marie-Pierre et al (1993) Can single-chain perfluoroalkylated amphiphiles alone form vesicles and other organized supramolecular systems? Angew. Chem. Int. Ed. Engl. 32 No.5:741-743.
Kunitake, Toyoki et al (1992) Synthetic bilayer membranes: molecular design, self-organization, and application. Angew. Chem. Int. Ed. Engl. 31:709-726.
Kunitake, Toyoki et al (1981) Formation of stable bilayer assemblies in water from single-chain amphiphiles . . . structure and the aggregate morphology. J. Am. Chem. Soc. 103:5401-5413.
Kunitake, T. et al (1982) Formation and enhanced stability of fluoroalkyl bilayer membranes. J. Am. Chem. Soc. 104:5547-5549.
Kuwahara, Hiroaki et al (1993) Self-organization of bilayer assemblies in a fluorocarbon medium. J. Am. Chem. Soc. 115:3002-3003.
Markowitz, Michael et al (1992) The influence of the polar headgroups of acidic diacetylenic phospholipids on tubule formation, microstructure morphology and Langmuir film behavior. Chemistry and Physics of Lipids 62:193-204.
Markowitz, Michael and Singh, Alok (1991) Self-assembling properties of 1,2-diacyl-sn-glycero-3-phosphohydroxyethanol: a headgroup-modified diacetylenic phospholipid. Langmuir 7:16-18.
Nakashima, Naotoshi (1985) Optical microscopic study of helical superstructures of chiral bilayer membranes. J. Am. Chem. Soc. 107:509-510.
Okahata, Yoshio and Kunitake, Toyoki (1979) Formation of stable monolayer membranes and related structures in dilute aqueous solution from two-headed ammonium amphiphiles. American Chemical Society 101:5231-5234.
Riess, J.G. et al (1991) Highly effective surfactants with low hemolytic activity. Angew. Chem. Adv. Mat. 3:249-25.
Riess, J.G. et al (1991) New perfluoroalkylated phosphatidylcholines as surfactants for biomedical applications. Barcelone 157-171.
Ringsdorf, Helmut et al (1988) Molecular architecture and function of polymeric oriented systems: models for the study of organization, surface recognition, and dynamics of biomembranes. Angew. Chem. Int. Ed. Engl. 27:114-158.
Schnur, Joel M. (1993) Lipid tubules: a paradigm for molecularly engineered structures. Science 262:1669-1676.
Schnur, J.M. et al. (1987) Lipid-based tubule microstructures. Thin Solid Films 152:181-206.
Schoen, Paul E. et al. (1985) Spectroscopic studies of polymerized surfactants: 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine. Journal of Polymer Science: Polymer Physics Edition 23:2203-2216.
Singh, Alok et al (1988) Self-assembled microstructures from a polymerizable ammonium surfactant: di(hexacosa-12,14-diynyl)dimethylammonium bromide. J. Chem. Soc. Chem. Commun. 18:1222-1223.
Yager, Paul (1986) Functional reconstitution of a membrane protein in a diacetylenic polymerizable lechithin. Biosensors 2:363-373.
Yanagawa, Hiroshi et al. (1989) Spontaneous formation of superhelical strands. J. Am. Chem. Soc. 111:4567-4570.
Giulieri Francoise
Krafft Marie-Pierre
Riess Jean G.
Zarif Leila
Alliance Pharmaceutical Corp.
Yamnitzky Marie
LandOfFree
Elongated microstructures from perfluoroalkylated amphiphiles does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Elongated microstructures from perfluoroalkylated amphiphiles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Elongated microstructures from perfluoroalkylated amphiphiles will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-650157