Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Reexamination Certificate
2006-07-04
2006-07-04
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
C435S252300, C435S252330, C435S325000, C435S320100, C435S254100, C435S254200, C435S254300, C435S348000, C435S254110, C435S419000, C435S254210, C435S254220, C435S254230, C435S254300, C435S254400, C435S254500, C435S254600, C536S023200
Reexamination Certificate
active
07070970
ABSTRACT:
The subject invention relates to the identification of four genes involved in the elongation of polyunsaturated acids (i.e., “elongases”) and to uses thereof. Two of these genes are also involved in the elongation of monounsaturated fatty acids. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomogamma linolenic acid (DGLA) and in the conversion of DGLA or 20:4n-3 to eicosapentaenoic acid (EPA). DGLA may be utilized in the production of polyunsaturated fatty acids, such as arachidonic acid (AA), docosahexaenoic acid (DHA), EPA, adrenic acid, ω6-docosapentaenoic acid or ω3-docosapentaenoic acid which may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
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Das Tapas
Huang Yung-Sheng
Leonard Amanda E.
Mukerji Pradip
Parker-Barnes Jennifer
Abbott Laboratories
Becker Cheryl L.
Prouty Rebecca E.
Swope Sheridan L.
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