Elimination of interference in diagnostic methods by peptides co

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 792, 435 793, 435 794, 435 795, 435 693, 435962, 436518, 530300, 530330, 530331, 530328, 530329, 514 12, 514 13, 514 14, 514 15, 514 16, 514 17, 514 18, G01N 3353, G01N 33543, C12N 1509, A61K 3800, A61K 3804

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061533939

ABSTRACT:
The invention concerns the use of peptides which are comprised essentially of D-amino acids to eliminate interference in diagnostic methods, a method for eliminating interference in diagnostic methods by peptides which are comprised essentially of D-amino acids as well as a reagent that eliminates interference containing at least one peptide which is comprised essentially of D-amino acids.

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Seidel, C., "Synthesis of a cyclic peptide for diagnostic use by oxidation of resin-bound intermediate," Peptides, pp. 236-237 (1990).
BACHEM Bioscience, Heidelberg.
Robertson, P. W., et al., Reduction in non-specific binding in enzyme immunoassays using casein hydrolysate in serum diluents, Journal of Immunological Methods, vol. 76, pp. 195-197 (1985).
Seidel, C., et al., Synthesis of a cyclic peptide for diagnostic use by oxidation of its resin-bound intermediate, Peptides, pp. 236-237 (1990).
Sieber, Peter, A new acid-labile anchor group for the solid phase synthesis of C-terminal peptide amides by the FMOC method, Tetrahedron Letters, vol. 28, No. 19, pp. 2107-2110 (1987).
Wang, Su-Sun, p-alkoxybenzyl alcohol resin and p-alkoxybenzyloxycarbonylhydrazide resin for solid phase synthesis of protected peptide fragments, Journal of the American Chemical Society, vol. 95, No. 4, pp. 1328-1333 (1973).

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