Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1994-12-29
1996-04-23
Jones, W. Gary
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435 691, 4352523, 4353201, 435 701, 536 235, 536 241, 935 39, 935 44, 935 73, 935 22, C12N 1563, C12N 510, C07H 2104
Patent
active
055102565
ABSTRACT:
The present invention is based upon the discovery that proteins made from genes that include the CD4 sequence in its cDNA can make additional polypeptides as a result of internal translation initiation. This invention is thus directed to DNA sequences which eliminate internal initiation expression in sCD4.
REFERENCES:
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Gerald Preibisch, et al., "Unexpected translation initiation within the coding region of eukaryotic genes expressed in Escherichia coli", Gene 72:179-186, 1988.
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Brunner David P.
Eckenrode Frances M.
Kirschner Richard J.
Mott John E.
Darnley, Jr. James D.
Jones W. Gary
Myers Carla
The Upjohn Company
Wright Debbie K.
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