Elevation of HDL cholesterol by 4-[(aminothioxomethyl)hydrazono]

Details Elevation of HDL cholesterol by 4-[(aminothioxomethyl)hydrazono] Elevation of HDL cholesterol by 4-[(aminothioxomethyl)hydrazono]

1998-06-11

1999-11-02

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

N-c doai

558445, 560 24, 560 27, 560 28, 560 29, 560 30, 560 31, 560 33, 560163, 560115, 514488, 514489, C07C25527, C07C27110, A61K 3127

Patent

active

059771704

ABSTRACT:
This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of the formula ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 are independently hydrogen, C.sub.1 -C.sub.6 alkyl or --(CH.sub.2).sub.0-6 Ph where Ph is optionally substituted by halogen, cyano, nitro, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, trifluoromethyl, C.sub.1 -C.sub.6 alkoxycarbonyl, --CO.sub.2 H or OH;

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