Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens
Reexamination Certificate
2007-09-11
2007-09-11
Le, Long V. (Department: 1641)
Chemistry: analytical and immunological testing
Involving producing or treating antigen or hapten
Producing labeled antigens
C436S081000, C436S082000, C436S096000, C436S173000, C435S006120, C435S007100, C435S007500, C435S007920, C435S810000, C435S975000, C435S973000, C530S405000, C530S412000, C540S474000
Reexamination Certificate
active
10854735
ABSTRACT:
The present invention provides compositions and methods for detecting, analyzing, and identifying biomolecules. More particularly, the invention provides Element Coded Affinity Tags comprising a metal chelate and a metal ion and methods of using the tags to detect, analyze, and identify biomolecules including polypeptides, nucleic acids, lipids, and polysaccharides.
REFERENCES:
patent: 5760191 (1998-06-01), Snow et al.
patent: WO 00/11208 (2000-03-01), None
Liu et al. Radiolabeling of monoclonal antibodies with metal chelates. Pure & Appl. Chem., 1991, vol. 63, No. 3, pp. 427-463.
Kramerov, A.A., et al., “Tissue L ocalization and Secretion of Mucin-D inDrosophila melanogaster,” Russian Journal of Developmental Biology(1997) 28(4): 227-234.
Aebersold, et al.; “Mass Spectrometry-based Proteomics;”Nature; Mar. 2003; pp. 198-207; vol. 422.
Butterfield, et al.; “Proteomics for the Identification of Specifically Oxidized Proteins in Brain: Technology and Application to the Study of Neurodegenerative Disorders;”Amino Acids; 2003; pp. 419-425; vol. 25; Austria.
Butterfield; “Proteomics: A New Approach to Investigate Oxidative Stress in Alzheimer's Disease Brain;”Brain Research; 2004; pp. 1-7; vol. 1000; Elsevier B.V.
Dalle-Donne, et al.; “Protein Carbonylation in Human Diseases;”TRENDS in Molecular Medicine; Apr. 2003; pp. 169-176; vol. 9; No. 4; Elsevier Science Ltd.
Gygi, et al.; “Mass Spectrometry and Proteomics;”Current Opinion in Chemical Biology; 2000; pp. 489-494; vol. 4.
Gygi, et al.; “Proteome Analysis of Low-Abundance Proteins Using Multidimensional Chromatography and Isotope-Coded Affinity Tags;”Journal of Proteome Research; Jan. 18, 2002; pp. 47-54; vol. 1; American Chemical Society.
Gygi, et al.; “Quantitative Analysis of Complex Protein Mixtures Using Isotope-coded Affinity Tags;”Nature Biotechnology; Oct. 1999; pp. 994-999; vol. 17.
Himmelfarb, et al.; “Albumin is the Major Plasma Protein Target of Oxidant Street in Uremia;”Kidney International; 2001; pp. 358-363; vol. 60; International Society of Nephrology.
Odetti, et al.; “Levels of Carbonyl Groups in Plasma Proteins of Type 2 Diabetes Mellitus Subjects;”Acta Diabetol; 1999; pp. 179-183; vol. 36.
Patterson, et al.; “Proteomics: The First Decade and Beyond;”Nature Genetics Supplement; Mar. 2003; pp. 311-323; vol. 33.
Ranish, et al.; “The Study of Macromolecular Complexes by Quantitative Proteomics;”Nature Genetics; Mar. 2003; pp. 349-355; vol. 33.
Tao, et al.; “Advances in Quantitative Proteomics Via Stable Isotope Tagging and Mass Spectrometry;”Current Opinion in Biotechnology; 2003; pp. 110-118; vol. 14.
Zhou, et al.; “Quantitative Proteome Analysis by Solid-Phase Isotope Tagging and Mass Spectrometry;”Nature Biotechnology; May 2002; pp. 512-515; vol. 20.
Butlin Nathaniel G.
Cheal Sarah M.
Corneillie Todd M.
Lebrilla Carlito B.
Lee Susan
Haq Shafiqul
Le Long V.
Regents of the University of California
Townsend and Townsend / and Crew LLP
LandOfFree
Element-coded affinity tags does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Element-coded affinity tags, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Element-coded affinity tags will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3763498