Electrosynthetic method of modifying biomolecules in particular

Details Electrosynthetic method of modifying biomolecules in particular Electrosynthetic method of modifying biomolecules in particular

1997-09-09

1999-05-18

Lankford, Jr., Leon B.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Enzyme treated

4351731, 20415782, 530345, 530350, 530402, C12N13/00

Patent

active

059050322

ABSTRACT:
Pendant groups in the alpha-amino acid monomer residues comprising a polypeptide molecule are selectively modified by applying an electric potential across an electrochemical cell containing the polypeptide.

REFERENCES:
patent: 5364851 (1994-11-01), Joran
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Brabec and Mornstein. Biochimica et Biophysica Acta. vol. 625, pp. 43-50, 1980 (ref 1980a).
Brabec and Mornstein. Biophysical Chem. vol. 12, pp. 159-165 1980 (ref 19806).
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"Electrochemical Oxidation of Proteins as a New Probe of Protein Structure,"Chemical Abstracts, vol.94, No. 25, Jun. 22, 1981, Columbus, Ohio, US; Abstract No. 20411m, V Brabec, p. 187.
"The Electrochemical Oxidation of Three Proteins; RNAse A, Bovine Srum Albumin and Concanavalin A at Solid Electrodes," Chemical Abstracts, vol. 94, No. 9, Mar. 2, 1981, Columbus, Ohio, US; Abstract No. 60173j, p. 245.
"Electrochemical Behavior of Proteins at Graphite electrodes. I. Electrooxidation of Proteins as a New Probe of Protein Structure and Reaction," Chemical Abstracts, vol. 93, ho. 25, Dec. 22, 1980, Columbus, Ohio, US; Abstract No. 234256k, p. 398.
"Electrochemical Behavior of Proteins at Graphite Electrodes. II. Electrooxidation of Amino Acids," Chemical Abstracts, vol. 93, No. 25, Dec. 22, 1980, Columbus, Ohio, US; Abstract No. 233235r, p. 296.
"Proteins Modified by Iodine Isotopes," Chemical Abstracts, vol. 85, No. 25, Dec. 20, 1976, Columbus, Ohio, US; Abstract No. 188160j, p. 178.

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