Electrospun nanofiber-based biosensor assemblies

Fabric (woven – knitted – or nonwoven textile or cloth – etc.) – Nonwoven fabric – Including strand or fiber material which is of specific...

Reexamination Certificate

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C428S375000, C442S330000, C442S334000, C442S351000, C138S140000

Reexamination Certificate

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07485591

ABSTRACT:
Electrospun nanofiber incorporating a binder (e.g., biotin) is used in the form of a nonwoven or composite with a substrate. The nonwoven and composite can be joined to biosensor, e.g., by binding the biotin to streptavidin and binding streptavidin to biotinylated detector, and because of the high surface area to volume of electrospun nanofiber provides increased sensitivity.

REFERENCES:
patent: 2006/0094320 (2006-05-01), Chen et al.
Baeumner, A., et al, “Nanofiber-Based Biosensors”, poster presented May 23 and May 24, 2005 at Cornell Center for Materials Research Polymer Outreach Program (POP) Symposium.

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