Radiant energy – Ionic separation or analysis – With sample supply means
Patent
1998-02-06
2000-03-28
Anderson, Bruce C.
Radiant energy
Ionic separation or analysis
With sample supply means
250281, B01D 5944, H01J 4900
Patent
active
060434872
ABSTRACT:
An electrospray ionizer which enables the operator to adjust the position of the glass capillary with respect to the metal tube to which a high voltage is applied while the sample solution is being nebulized and ionized at the fore end of the glass capillary. The electrospray ionizer is composed of: a glass capillary for allowing the sample solution to flow out from its fore end; a metal tube surrounding the fore end part of the glass capillary for generating an irregular electric field at around the fore end of the glass capillary; a first pipe, or a guide pipe, made of a non-conductive material for holding the back end of the metal tube and extending backward; a second pipe, or a seal pipe, for loosely holding the glass capillary further back along the first pipe; and a joint for connecting the first pipe and the second pipe. Consequently, the position of the glass capillary is loosely fixed with respect to the metal tube. Thus by manipulating the back end of the glass capillary to slide the glass capillary in the second pipe, it is possible to change the position, or the length of the extension d, of the fore end of the glass capillary with respect to the metal tube. This enables the operator to adjust the extension d so that the amount of ions generated at the fore end of the glass capillary is at its maximum while the electrospray ionizer is working and the metal tube has a high voltage applied to it, whereby the sensitivity of the liquid chromatograph using the electrospray ionizer of the present invention is greatly improved.
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Anderson Bruce C.
Shimadzu Corporation
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