Electrospray ionization using pointed fibers

Radiant energy – Ionic separation or analysis – Methods

Reexamination Certificate

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C250S288000, C250S281000

Reexamination Certificate

active

07087895

ABSTRACT:
A pointed carbon fiber electrospray ionization emitter has a length of electrically conductive fiber that is present within a lumen of a microfluidic device, and protrudes from the terminus. A point is present on an end of the electrically conductive fiber, or the electrically conductive fiber is otherwise sufficiently small on the end to create a desired spray. A conductor supplies electrical current to the electrically conductive fiber. Fluid to be sprayed is transported through the lumen and out of the terminus of the lumen, and an electrical field established by the conductive fiber distributes and sprays the fluid. The emitter is rugged and is able to generate stable electrospray over a wide range of flow rates, voltages, and surface tension variations.

REFERENCES:
patent: 5824026 (1998-10-01), Diaz
patent: 5836946 (1998-11-01), Diaz et al.
patent: 6670607 (2003-12-01), Wood et al.
patent: 6764720 (2004-07-01), Pui et al.
patent: 2002/0003209 (2002-01-01), Wood et al.
patent: 2004/0206399 (2004-10-01), Heller et al.
patent: 2005/0064168 (2005-03-01), Dvorsky et al.
patent: 2006/0057556 (2006-03-01), Janini et al.

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