Electrospray ionization mass spectrometer with new features

Details Electrospray ionization mass spectrometer with new features Electrospray ionization mass spectrometer with new features

1990-01-22

1990-12-11

Berman, Jack I.

Radiant energy

Ionic separation or analysis

With sample supply means

250281, H01J 4904, H01J 4910

Patent

active

049773208

ABSTRACT:
An electrospray ion source is designed for ready and simple plugging into commercial mass analyzers for mass spectrometric analysis of organic molecules. The electrospray is carried out is the ambient air and the ions and other charged species enter the mass analyuzer through a long metal capillary tube and three stages of differential pumping. The use of the long tube allows (a) convenient injection of the ions into the mass analyzer (b) optimization of the spray by direct visualization in the air (c) efficient and controlled heat transfer to the droplets and (d) efficient pumping of the region between the capillary exit and the skinner. Desolvation of the solvated ions is carried out using a combination of controlled heat transfer to the charged droplets during the transit through the tube and collisional activation in a region of reduced pressure. Desolvation with this system does not involve use of a strong countercurrent flow of heated gas. The system also may be used to obtain the collisional activated fragmentation spectra of molecule ions. The use of a metal capillary tube avoids complications from charging that arise from the use of dielectric capilliary tubes.

REFERENCES:
patent: 4209696 (1980-06-01), Fite
patent: 4542293 (1985-09-01), Fenn et al.

Affiliated with

Also associated with

Rating

Electrospray ionization mass spectrometer with new features does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Electrospray ionization mass spectrometer with new features, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Electrospray ionization mass spectrometer with new features will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-391536