Electrospray ion source apparatus

Radiant energy – Ionic separation or analysis – With sample supply means

Reexamination Certificate

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Reexamination Certificate

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11128653

ABSTRACT:
An electrospray interface for forming ions from a liquid sample in a mass analyzing system includes a capillary tube having a free end for introducing a spray of droplets into an ionization chamber, a first gas passageway positioned near the capillary tube for directing a first gas stream into the ionization chamber, and a second gas passageway positioned more remotely from the capillary tube for directing a second, low-velocity gas stream into the ionization chamber. The second gas stream is heated to increase the droplet desolvation rate. A heated sampling capillary having an end extending into the ionization chamber guides the analyte ions toward a mass analyzer and evaporates the solvent from any incompletely desolvated droplets entering the sampling capillary.

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Balogh, Michael P., “Source Design and the Utility of Multimode Ionization,” www.chromatographyonline.com, LGCG North America, vol. 21 ( No. 10), p. 984-991, (Oct. 2003).

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