Electrospray device

Radiant energy – Ionic separation or analysis – With sample supply means

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

H01J 4910

Patent

active

061406406

ABSTRACT:
A non-reactive electrospray needle structure that can be used with relatively low electrical potential introduced externally at a selectable location along the length of the needle structure. The electrospray device or apparatus includes a non-conductive tube with an inner diameter, with one end of the tube having a reduced inner diameter thereby forming a tip. The tube is configured to have a fracture in it, positioned a predetermined or selectable distance from the tip. An electrically conductive path, such as a wire or electrode, is provided external to the tube and proximate to the fracture. A collar surrounds the tube proximate the fracture. The electrically conductive path provides a voltage potential to charge the spray. The collar maintains the conductive path in place, seals the tube at the fracture, and provides structural strength. In one embodiment, the tube is packed with a binding material to form a column bed.

REFERENCES:
patent: 3652248 (1972-03-01), Loxley et al.
patent: 3887221 (1975-06-01), Young
patent: 4025327 (1977-05-01), Harris
patent: 4529230 (1985-07-01), Fatula, Jr.
patent: 4706256 (1987-11-01), Sheng et al.
patent: 4787656 (1988-11-01), Ryder
patent: 4877270 (1989-10-01), Phillips
patent: 4908116 (1990-03-01), Zare et al.
patent: 4989974 (1991-02-01), Anton et al.
patent: 5223226 (1993-06-01), Wittmer et al.
patent: 5288113 (1994-02-01), Silvis et al.
patent: 5395521 (1995-03-01), Jagadeeswaran
patent: 5423513 (1995-06-01), Chervet et al.
patent: 5487569 (1996-01-01), Silvis et al.
patent: 5540464 (1996-07-01), Picha
patent: 5572023 (1996-11-01), Caprioli
patent: 5744100 (1998-04-01), Krstanovic
Authors: Per E. Andren and Richard M. Caprioli Titled: In Vivo Release and Metabolism of Neurotensin in Rat Brain by Microdialysis and Nano-LC/Micro-ES/MS Conference: 42.sup.nd ASMS Conference on Mass Spectrometry -p. 347.
Authors: Mark R. Emmett and Richard M. Caprioli Titled: Release of Endogenous Methionine Enkephallin in Brain Using Microdialysis and Capillary LC, Micro-ES/MS/MS Conference: 42.sup.nd ASMS Conference on Mass Spectrometry -p. 420.
Authors: Richard M. Capriloli, Mark E. Emmett and Per E. Andren Titled: Micro-Electrospray: Ultra-High Sensitivity For Peptides (Zeptomoles/Attomoles) and Proteins (Attomoles/Femtomoles) Conference: 42.sup.nd ASMS Conference on Mass Spectrometry -p. 754.
Authors: Mark R. Emmett and Richard M. Caprioli Titled: Micro-Electrospray Mass Spectrometry: Ultra-High-Sensitivity Analysis of Peptides and Proteins Article: Journal Am Soc Mass Spectrom 1994, 5, 605-613.
Authors: Per E. Andren, Mark R. Emmett and Richard M. Caprioli Titled: Micro-Electrospray: Zeptomol/Attomole Per Microliter Sensitivity For Peptides Article: J. Am Soc Mass Spectrom 1994, 5, 867-869.
Authors: Mark Ralph Emmett Titled: Development of Micro-Electrospray Mass Spectrometry for Ultra High Sensitivity and Application in the Study of Drugs of Abuse on Endogenous [Met].sup.5 -Enkephalin Release Dissertation: 1995, Presented to the Faculty of the University of Texas at Houston Graduate School of Biomedical Sciences.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Electrospray device does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Electrospray device, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Electrospray device will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2054590

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.