Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1987-08-31
1992-07-07
Niebling, John
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435287, C12N 1300
Patent
active
051282577
ABSTRACT:
Process and apparatus for electroporation of cell suspensions and cells adhered to a surface wherein at least two simultaneous and directionally distinct electric impulses are used to transfect a biological substance into a cell.
REFERENCES:
patent: 4695547 (1987-09-01), Hilliard et al.
patent: 4764473 (1988-08-01), Matschke et al.
George W. Bates, "Electrical fusion for optimal formation of protop last heterokaryors in Nicotiana" Planta. 165 (1985) 217-224.
Berg, H. "Electrotransfection and electrofusion of cells and Electrostimulatior of their Metabolism" Studio Biophsica. vol. 119 (1987) pp. 17-29.
Zimmermann, U. and Vienken J. "Electric Field-Induced Cell to Cell Fusion" J. Membrane Bio. 67, 165-182 (1982).
Niebling John
Starsiak Jr. John S.
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