Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...
Patent
1994-01-21
1996-04-16
McDermott, Corrine M.
Surgery
Means for introducing or removing material from body for...
Treating material introduced into or removed from body...
604 21, 604101, 607116, A61M 3100
Patent
active
055077242
ABSTRACT:
A catheter device having a plurality of axially extending, circumferentially spaced electrodes carried thereby, infusion means for infusion of fluid medium for carrying genes and drugs, and expandable sealing means at each end of the electrodes for sealing off and confining the therapeutic medium to the area to be treated is inserted into a selected blood vessel of a patient and advanced to a preselected location within the blood vessel where cells on or near the wall of the vessel are to be treated. Once in place, the catheter device is expanded so that the plurality of axially extending, circumferentially spaced electrodes carried thereby are in contact with the inner wall of the blood vessel and seals at each end of the electrodes expand and seal the catheter device in the preselected location. A quantity of therapeutic genes or drugs is infused into the area of the electrodes via a tube and a conventional pump. A power pack connected to the electrodes is energized subjecting the cells to electric fields of predetermined amplitude and duration making the walls of the cells transiently permeable to enabling therapeutic genes or drugs carried by the fluid medium to enter the cells without killing them.
REFERENCES:
patent: 3680544 (1972-08-01), Shinnick et al.
patent: 4709698 (1987-12-01), Johnston et al.
patent: 5002527 (1991-03-01), Reller et al.
patent: 5042975 (1991-08-01), Chien et al.
patent: 5098843 (1992-03-01), Calvin
patent: 5117828 (1992-06-01), Metzger et al.
patent: 5137817 (1992-08-01), Busta et al.
patent: 5154165 (1992-10-01), Elliott et al.
patent: 5236413 (1993-08-01), Feiring
patent: 5256141 (1993-10-01), Gencheff et al.
patent: 5279046 (1994-01-01), Mische et al.
patent: 5282785 (1994-02-01), Shapland et al.
patent: 5286254 (1994-02-01), Shapland et al.
patent: 5423744 (1995-06-01), Gencheff et al.
Crandell Lois J.
Hofmann Gunter A.
Genetronics Inc.
McDermott Corrine M.
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