Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...
Patent
1995-02-09
1998-09-22
Tsang, Cecilia J.
Chemistry: electrical and wave energy
Processes and products
Electrophoresis or electro-osmosis processes and electrolyte...
204452, 204601, 204603, 2041821, 2041801, 2041828, 204299R, 435 74, C25B 700, G01N 33573
Patent
active
058109854
ABSTRACT:
Disclosed are methods of electrochemical analysis of an analyte in a sample. The methods include providing a sample comprising an analyte, and introducing the sample into a capillary tube containing electrophoretic running buffer and a reactant. According to the methods of the invention, one or both of the analyte and the reactant is electrically charged. Chemical contact between analyte and reactant induced by their relative electrophoretic mobility results in the breaking or formation of a covalent bond of one of the analyte or the reactant to produce a detectable product. The methods also include the steps of imposing along the length of the capillary tube an electric current for a time sufficient to bring into chemical contact within the tube analyte and reactant so as to allow formation of product, and detecting the product.
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Bao Jianmin
Harmon Bryan Joseph
Patterson Dale Hansen
Regnier Fred E.
Delacroix-Muirheid C.
Purdue Research Foundation
Tsang Cecilia J.
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