Electrophoretic method for the isolation and separation of micro

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

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435 30, 435 34, 4351739, 356344, C12Q 102, C12Q 124, C12N 1300

Patent

active

055784607

ABSTRACT:
The present invention sorts microorganism populations from a mixture which contains more than one microorganism population. Microorganisms of different types vary in size, shape, and surface charge characteristics. These characteristics we believe contribute to the rate of migration for microorganisms under the influence of an electric field. Microorganisms of the same population (genus and species) will migrate similarly. By applying an electric field in a direction opposite the direction of fluid flow, separation is enhanced.

REFERENCES:
patent: 5324401 (1994-06-01), Yeung et al.
McCormick, R., Capillary Zone Electrophoretic Separation of Peptides and Proteins Using Low pH Buffers in Modified Silica Capillaries, Anal Chem 1988 60, 2322-2328.

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