Electrophoretic cuff apparatus drug delivery system

Details Electrophoretic cuff apparatus drug delivery system Electrophoretic cuff apparatus drug delivery system

1998-06-12

1999-11-09

Bockelman, Mark

Surgery

Means for introducing or removing material from body for...

Infrared, visible light, ultraviolet, x-ray or electrical...

604 67, 607148, 607149, 607152, 607153, A61N 130

Patent

active

059831340

ABSTRACT:
A flexible cuff for wrapping around a part of a limb, that is comprised of multiple biosensing patch units of a required size and shape to fit the body contour for applying to an area of skin. The cuff has an array of flexible porous (polymer) electrodes held at constant potential with alternating polarities. A network of supply tubes connected to an external liquid reservoir provides a slow supply of medicated fluid to each electrode. A pump/titration regulator is in communication with the transdermal electrode to regulate permeant flow to the skin. An electric and an electromagnetic field applied through the cuff then causes the drug to be rapidly absorbed throughout the skin. The electrodes within the cuff, or the applicator pads which it is comprised of, can be additionally used for applying electromagnetic, Transcutaneous Nerve Stimulation, and for Electrical Muscle Stimulation. Alternatively, the cuff can be used to assist rehabilitation exercise therapy conditioning in combination with Electrical Muscle Stimulation.

REFERENCES:
patent: 4729377 (1988-03-01), Granek et al.
patent: 4968297 (1990-11-01), Jacobsen et al.
patent: 5037380 (1991-08-01), Jacobsen et al.
patent: 5823989 (1998-10-01), Ostrow

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