Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Boron containing doai
Patent
1997-08-01
2000-05-09
Ambrose, Michael G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Boron containing doai
546 13, 548110, 549 4, 558 5, 558288, 558298, 562 7, A61K 3169, C07F 504, C07F 502
Patent
active
06060462&
ABSTRACT:
This invention relates to electrophilic dipeptide analogs conjugated to an N,N-disubstituted .alpha.-amino acid as inhibitors of trypsin-like serine protease enzymes.
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patent: 5187157 (1993-02-01), Kettner et al.
patent: 5252566 (1993-10-01), Shuman
Gesellchen and Shuman J. Med. Chem 36, 314-319 (1993).
Balasubramanian, et al. (J. Med. Chem 36, 300, (1993)).
Abelman Matthew Mark
Amparo Eugene Cruz
Cacciola Joseph
Fevig John Matthew
Galemmo, Jr. Robert Anthony
Ambrose Michael G.
DuPont Pharmaceuticals Company
Reinert Norbert F.
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